Betadine Solution is a topical, water-based antiseptic microbicide used to kill bacteria, fungi and viruses. Contains 5% povidone-iodine (0.5% available iodine). Use full strength for: â€¢ Preoperative prepping of skin and mucous membranes. â€¢ Preventing bacterial infection. â€¢ Emergency antisepsis of minor lacerations, abrasions, and burns. â€¢ Postoperative application to surgical incisions.